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221b Baker St. is an adventure game developed by IntelliCreations and published by Datasoft for the Atari 8-bit, Apple II, DOS, Commodore 64, and Atari ST platforms.

The game revolves around private detective Sherlock Holmes and his efforts to crack a case that's stumped Scotland Yard. The game presents a different case each time it is played, which is randomly generated. Using clues, Sherlock Holmes must identify the correct suspect.

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