The technological visionary has dealt with health issues for close to a decade, going on a medical leave of absence this past January.
He continued to be a public figure for Apple until announcing his retirement in August.
"Steve’s brilliance, passion and energy were the source of countless innovations that enrich and improve all of our lives. The world is immeasurably better because of Steve," said a statement from by Apple's board of directors. "His greatest love was for his wife, Laurene, and his family. Our hearts go out to them and to all who were touched by his extraordinary gifts."
The company announced the latest iteration of the iPhone yesterday, the iPhone 4S. It goes on sale later this month.
Apple is collecting thoughts and memories of Jobs through the email address firstname.lastname@example.org.
Thanks for everything, Steve.