“Attention: After a long internal debate Nintendo has decided NOT to allow the Binding of Isaac on the 3ds. :(“ said the designer. “As many assumed the reasons were due to the games "questionable religious content". Thank GOD Steam exists!”
The Binding of Isaac is not the next game from Team Meat, McMillen’s other outfit that produced 2010’s Super Meat Boy. Team Meat is working on another project, and McMillen made The Binding of Isaac as a post-release breather. The game’s best described as, well, a Zelda-inspired roguelike.
You should really play it.