@MikkaQ: See, the story in Brotherhood is my favourite in the whole series. Just a nice concise story of Ezio building alliances to take out the Borgia family within a singular environment. They do a spectacular job introducing why you should hate them, then do a great job spotlighting each member.
I never really connected with Rodrigo. I think they played the mystery card up a bit too much, and almost didn't give you enough of him as a character. And Assassin's Creed 2 spans too great a length of time, as does the actual gameplay time. It's exhausting and unnecessarily long-winded.