I agree that the comments can get pretty stupid, and I absolutely hated all the people complaining in the P4 and Deadly Premonition runs because other than Brad being Brad, they played those games like any normal person would play a game their first time through. While I am really enjoying the Chrono Trigger run and most of the comments are, like past endurance runs, stupid and bitchy, there are some valid complaints thrown in with the inane ramblings. The biggest I've had is the fact that for a good 20 episode stretch, it seemed like they weren't reading anything and didn't seem to really care about the story, which is probably the best story in a 16-bit game. They definitely did get better about reading as it went on, and while I consider this ER to be in 4th place as far as best ERs go (#1:P4 #2:VJ DP #3: BR DP), it is still great and better than just about any Let's Play you'll find on the internet.
It's alright. However, if you've already played Chrono Trigger then it's not that interesting since you know what's going to happen. It's not nearly as crazy as P4 or Deadly Premonition, meaning that there's less material to make fun of.
And as others have said, don't read the video comments. Patrick and Ryan are pretty much playing through it blind - Ryan's never played it and Patrick has almost forgotten everything about it. They don't find all the secrets, they make mistakes and they play it like any other human being and for some reason that infuriates some people who bitch and moan about how they don't play it in a "perfect" way. Somehow I doubt the complainers played it "perfectly" the first time they played it.