Probably solo first, but that's only because my friends live in different time zones and therefore will get a head start on me. Once we're both up I'll probably play with them, since I know they won't be skipping the cut scenes.

That said, the only real reason to play solo is for the story. Once that's out of the way playing in groups is the best way to make it up through NM and Hell, and then finally inferno

First run will be solo. I want to soak in all the atmosphere and story and not get rushed by others who just wants to finish the game as fast as possible.

I'm going to test out some of classes first and play solo with which ever one I like the most. I'll jump into MP for the harder modes.

Solo

Solo so I can focus on the story. I'll probably beat it before my friends do, then I'll join one of their games.

Solo - don't really see the enjoyment in playing with absolute randoms. That said, I might start an Inferno run with some of my staff when I get it unlocked and the like.

I happen to really like Diablo's story. So yeah, I'll be mostly soloing.

I've always been one of the relatively rare people that mostly played Diablo 2 solo and preferred it that way, and I'll be starting out that way in D3 to get a feel for things, as well. But I'll be playing another character in MP basically concurrently, I think, since I have a friend that I want to play it with.

Solo then with friends. I don't play with random people usually.

Anyone who is interested playing multi and not skipping any cut scene stuff feel free to add me/contact me for a game. Battletag is jordanado#1197

No real desire to play the game, but a friend is going nuts waiting to play this game so I'm playing it with him because I would never hear the end of it if I didn't. Played the beta and only cared for the Witch Doctor. So I will do co-op with said class/friend and then probably never touch it again.

Solo initially then I'll run with other duders.