| Spyro the Dragon first in Spyro the Dragon | 3 |
| Moneybags | 3 |
| Mary Jane Watson first in The Amazing Spider-Man vs. The Kingpin | 2 |
| Dr. Eggman first in Sonic the Hedgehog | 2 |
| Wolverine first in X-Men | 2 |
| Vulture first in The Amazing Spider-Man vs. The Kingpin | 2 |
| Sonic the Hedgehog first in Sonic the Hedgehog | 2 |
| Spider-Man first in Spider-Man | 2 |
| Shocker first in Spider-Man and the X-Men: Arcade's Revenge | 2 |
| Rudolf Steiner first in Phantasy Star II | 2 |