Other than the insane amount of screen tearing (I'm about to go to the nvidia control panel, but I'm guessing there will be a patch to fix this), this game is running beautifully at 1080p all maxed out.
Expect a good amount of these shots to be opening stuff cuz I only just now installed it.
EDIT: OK, so enabling v-sync through the control panel fixed the screen tearing problem. Looks like the in game v-sync toggle is just broken. Now the game is running perfectly.
I'll post more as I play more, feel free to add some.