After the intro music and after the outro music wouldn't bother me, but please dont interrupt in the middle of the podcast for ads. That would be the worst. They have to find advertisers that let them swear as well.
If they will do it much like old-timey radio did where they actually cut their own promos and did their own scripts for it, then read it on the air...
...then hell yes, I would love it.
"E-MAILS! brought to you by the fine people at Doritos...whom Brad Shoemaker is leaving Giant Bomb to work for."
EDIT:that was poorly said: was it not just a few weeks ago, during the whole "journalist integrity" thing, that Jeff more or less said, if you don't trust them (the bombers) to do right by us (the viewers) then why are you still around? if they need to advertise on the 'cast I trust that they will do it in the most responsible and unobtrusive way possible.
I'm against the idea seeing as I'm currently paying to view an ad free site. I'm a gold member and for a good amount of time I haven't felt the premium content hasn't been worth it, so if they suddenly started putting ads in the Bombcast I would probably take my money elsewhere. I mean at least at the moment I'm getting an ad free Bombcast for my money even when the premium content seems to dry up pretty badly at times. If they want to include an ad free version in the subscription then fine, but force ads on everyone and that might be the deciding factor the next time my subscription is up for renewal.
As long as it's nothing more than a 60 second bumper or them saying this episode of bombcast is sponsored by _________, it doesn't really bother me. Go back and listen to some old episodes of TalkRadar. They had shows that were sponsored and it was pretty non intrusive.
The website has ads and optional subscriptions. If they promoted the site and its content more on the 'cast, wouldn't that benefit both sides without having to resort to advertising on the 'cast?
Ads during the 'cast feel dirty and can cause people to question whether they can trust the guys to speak honestly, but a segment talking about new content on the site is more appealing even if it's done to direct listeners to ads.
"Ugh, another ad." vs. "Oh, this article or piece of community content sounds neat. I'll go check it out." Both see the user served with advertising, but the latter results in a happier user.
But hey, I'm no marketing guy. Just a guy.