I am currently receiving an Error 500 on certain sections of the website:
The homepage (http://www.giantbomb.com/)
The new releases section (http://www.giantbomb.com/new-games/)
The reviews section (http://www.giantbomb.com/reviews/)
The videos section (http://www.giantbomb.com/videos/)
This includes all sub-pages of each section for example a video page of a quick look or a review of a game will receive the same HTTP 500 error.