Despite them not really being connected, the gear thing (about remembering where you got an item) made me think of Titan Quest a bit. I remember enemies who would drop good equipment actually had it on visually (and even had the stats from it). So if some guy zapped you to hell and back with some lightning staff, he would actually drop it. The fact that this was all randomly generated was pretty neat, as the mods that increased (rare) item drop rate would actually make enemies better geared as well, which was a ton of fun. They're doing the same thing again for Grim Dawn, which is cool.
As for Destiny, the multiplayer sounds original (especially for the genre), but I hope for a Souls-like "invasion" equivalent as well. It would be an interesting addition/opposition to other people being able to help you out in your storyline.