I'm a shit boring white dude in his twenties, living with two nice ladies. We've all got weird schedules, but when we do hang out we can usually agree on fairly nerdy fare (Doctor Who, anime, tabletop roleplaying, etc.) Two of us were pretty into Final Fantasy and Japanese RPGs as teens.
This other gal has recently outed herself to us (we had our suspicions). She's put it to us that the reason she doesn't really enjoy video games is a lack of anything even resembling a strong lesbian lead character. She plays a lot of doujin dating sims and enjoyed Saint's Row IV for the first hour or so, until it became too tough for her to hang with (not an expect with a dual-stick controller). She has jammed on some Let's Play stuff for Bioshock Infinite and other story-heavy games, and put it to myself and my other roommate that she'd be down to essentially "drive" one of us through a game to get to story bits.
Right now my best bet is the Mass Effect trilogy, which allows for all manner of queer characters. There's also (stick with me) Final Fantasy X-2, which at least tells a story about an all-female J-pop band with costumes as a mechanic. She's very into musicals. Also Madoka Magika.
What other games do you think would be worth looking into to entertain my good, recently outed friend?