What game do you think they'll choose?
My pick is Assassin's Creed III, and I predict it'll be between it and Borderlands 2. Jeff loved the first Borderlands, and I predict he'll love this one and talk it up. But I don't think he'll be able to get the rest of the crew behind it. Both Jeff and Ryan love the AC story. On the 2009 podcast, Jeff said about Assassin's Creed II, "And I love that ending. I love it, I love it, I love it." And Ryan's GOTY in 2010 was Assassin's Creed: Brotherhood.
Other than Borderlands 2, I don't see much competition. Halo 4 and Far Cry 3 stand out. I doubt they'll get into Resident Evil 6. Diablo III will win PC game, but they're not so into it that it'll win GOTY.
What's your pick? Feel free to make other, related predictions.