Is there a huge franchise that you've missed entirely?

not really sure why i just thought of this, but for me it's Pokemon.  not saying i want to run out and play it, but that is one gigantic franchise that i haven't played one second of 
 
and WoW, i have successfully steered clear of WoW thus far.  i saw what that game did to some of my friends and i play WAY TOO DAMN MANY GAMES on every platform to let one single game dominate my everything.  also, i enjoy seeing the sun from time to time =)

Metal Gear Solid.  Never played one except for a few minutes of 4's demo.  Everyone talks about the story so much that I feel I'd have to go back to 1 or 2 to get the full effect.  Since I doubt I'll ever do that, this is a major franchise I'll likely miss.  That is unless Konami reboots the series or spins something off that's fresh but based in the MGS universe. 

i'm getting into it now because i just got a ps3 this christmas but metal gear solid. this and elder scrolls. fallut was on the list till i got new vegas for ps3 as well for christmas so yea. lol

I haven't played any Uncharted games yet, I actually wanted to and ordered a copy of the game but received an empty box. Still hopefully I'll get to give it a go eventually.

Never played a single Metroid game.

probably mass effect
 
bioshock
 
not had time to play them
 
and i probably never will at this rate

Anything only on PlayStation (Metal Gear [for the most part, at least], Uncharted, Killzone, Resistance, etc.), Civilization, Resident Evil, Starcraft...

Metal Gear Solid, and Resident Evil are the only two I can think of. 

Off the top of my head: 
 

• Ratchet and Clank - One of the many PS2 era franchises I missed and wished I had of played.
• Sly Cooper - Same as above
• Jack and Daxter- Same as above.
• Metroid - Zero interest in this franchise.
• Castlevania- Same as metroid.
• Gran Turismo- Don't care for racing games or cars. The game always looked extremely  boring to me.
• Street Fighter- I think I may have played a game or two in a local bowling alley once, but I can't remember.
• Max Payne- Always looked cool, but never enough to play for some reason.
• Diablo- I just can't stand all the clicking the game requires.
• Uncharted- Didn't have a PS3 until recently, and I'm not a fan of shooters on consoles so I'm waiting for the bargain bin or combo pack.
• Metal Gear- I kind of played that demo of 2 and I could never understand why people liked it.
• Unreal Tournament- I was a Quake guy.
• Prince of Persia- Watched videos and people playing it and it never did anything for me.
• Resident Evil- I played and beat 5, but it did nothing for me. Haven't played any of the other games any serious amount ether.

• Fallout
• Elder Scrolls
• King's Quest
• Space Quest
• Police Quest
• Simon the Sorcerer
• Syberia
• Assassin's Creed
• Persona
• Call of Duty
• Tex Murphy
• Civilization
• Zork
• Myst

Metroid and Zelda. :/

more people need to have a metal gear summer

  i've never played Halo, and never felt the need for it.  When it came out i was playing Quake III Arena, and Unreal Tournament

First thing that comes to mind is Final Fantasy... only played about 5 mins of a FF8 Demo, and it didn't really do it for me.

Anything from Nintendo since the early nineties.

 Biggest gaps in my gaming knowledge are:

Half Life
Doom
Duke Nukem
Metroid
Zelda
 
Yes i know, let the stone throwing commence!

Doom 
Tekken 
Final Fantasy 
Castlevania 
Duke Nukem 
Gran Turismo 
Resident Evil 
Any  Blizzard game. 
 
There a huge list of others but I CBA to write them out. I have played Gran Turismo round someone's house and I've played the Resident Evil 5 demo but nothing more. I've also never owned a Zelda game.

Don't have a PS3... so everything on that.

Final Fantasy.. I tried playing it on the Game Boy but never really got the hype. Also Resident Evil, but simply because I've seen people struggle with the controls and I don't wanna even try. 

Metroid

Assassin's Creed.

I've skipped out on Mass Effect entirely. I hadn't even heard of the first one for a while, but when I did, it was during a time I had a pretty ridiculous backlog of games going, and a 20 hours space RPG isn't something I felt I needed to invest in at the time. I've kind of cleared things up, but I never went back...

"I've skipped out on Mass Effect entirely. I hadn't even heard of the first one for a while, but when I did, it was during a time I had a pretty ridiculous backlog of games going, and a 20 hours space RPG isn't something I felt I needed to invest in at the time. I've kind of cleared things up, but I never went back... "

I never played an Assassin's Creed game - and I don't know if I ever will. 
Fable comes to mind, as well. Don't really care for that franchise.

I never played a single CoD game, and am never going to... Not really into FPS's, and even if I was I'd probably choose a Sci-Fi one over a Historical or Modern Military one, like Bioshock.
Oh... also, Bioshock!

Castlevania.

Fable, Zelda, metal gear, and Uncharted

Anything japanese except MGS, played some Wind Waker and Gran Turismo (1) though. I'll admit it, I loathe pretty much all forms of japanese game design. I don't really know why I love MGS. 
 
Other than that, most series that started on the PS3, or continued for that matter - never played God of War nor Killzone. Also, most newer console exclusives, since I sold my 360 a couple of years ago and now exclusively play on PC. There's only one series I really regret missing though, and that's Baldur's Gate. Was too damn young when it came out, and now it's just very, very old.

I know it's a relatively recent franchise, but Uncharted would be the one series that makes me -sorta- wish that I owned a PS3.

Mass Effect, and probably the biggest franchise of the moment: CoD, since CoD became what Alex Navarro would call A Thing.  Last title I touched was CoD3. Oh yeah, and Assassin's Creed.

A ton. The biggest I can think of right now are God of War and Mass Effect. (I ordered Mass Effect a few days ago, though)

Never had much interest in Call of Duty, played the demo for 2 many years ago, don't remember much from it. 
 
Mass Effect on the other hand I have been interested in a while and just bought the first one on Steam. 
 
Edit: Oh and Guitar Hero/Rock Band and all that junk.

Plenty, but the main one to me is Mass Effect..... tried to play the first one, but got tired really quickly.  I may give it another go sometime soon....... I won't bet on that feeling being acted upon though.

Zelda. Tried getting into it now. Didn't like it much.

Probably. There's Mass Effect, Tomb Raider, kinda (I played a few minutes of the first before I realized that the games aren't good, and it froze), um....that's all I can think of, at the moment.

I have never played a God Of War game and I think thats about it.

Gran Turismo, Dragon Quest, Pokemans, Metal Gear Solid, Final Fantasy

Fable, Mass Effect,  Final Fantasy, Zelda, Metroid, any of the major PS2/PS3 franchises that never came to the xbox since I never owned either console, Bioshock, and many more I cant think of.

metal gear solid 
 
final fantasy 
 
mortal combat 
 
anything mario 
 
anything donkey kong 
 
zelda

"....anything mario...."

Final Fantasy 
Zelda  
WoW 
Diablo 
Castlevania 
Metroid.... Tons more but i don't wanna list them all.

Gran Turismo
God of War
Gears of War
Guitar Hero
 
Yes, it's just a coincidence they all begin with the letter G. 

Mass Effect, Max Payne, Doom (Though I have now purchased these in the steam sale), all Blizzard titles.

Mass Effect and Assassin's Creed. I plan on getting to both at some point.

• Gran Turismo
• Forza
• Any sports franchise with the exception of NHL
• Doom
• Max Payne
• Uncharted
• Killzone
• MotorStorm
• Tekken

The people who are saying they've never played Doom make me very sad, as its one of my favorite franchises. That said, I never managed to get into Quake. 
 
I've never managed to play any Blizzard games other than Justice League Task Force and StarCraft 2 (which I still played very little of). I've also managed to avoid Call of Duty.

"....I'm going to say Zelda as well, since the last Zelda game I played was Adventure of Link, and that was 20 years ago "

I did play some of 12, but I don't think it really counts, so Final Fantasy.