That's a really tough question, maybe you could argue anything with a re-animated corpse or monster has lovecraftian themes, as for games featuring the Necronomicon, i cant think of any of the top of my head, and Ive played a lot of video games over the years.
Clive Barkers Undying has some horror and Occult themes, don't recall the Necronomicon in the game itself, although there is certainly parallels to that kind of lore.
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