Dead Space 2 I suppose, though I never played the first one (I really should, though). Portal never really grabbed me the way it did a lot of people, I mostly found myself just getting frustrated with it and consulting a guide. I would say Gears 3 but looks like that isn't happening anymore...Fuckin' Microsoft..
Good poll. Dragon Age II in mine (I mean, that was a no-brainer for me - look at my avatar) from this list. Honestly, it tops my overall most wanted for 2011 list.
That said, I know it doesn't have a absolute date yet, but Witcher 2: Assassins of Kings often changes places with DA2 in terms of my hype.
Shogun 2: Total War is also up there as well. Again, though, no firm date yet other than "Spring 2011".
Ah hell, might as well link my list for my top 5 for 2011.
Dragon Age 2 of course. Bioware makes their sequels times better than the original and I hope they can do it again. Seriously, Baldur's Gate - awesome, Baldur's Gate 2 - arguably the best RPG ever made; Mass Effect - awesome, Mass Effect 2 - better than ME in almost every way.
Anyone know if Brink is still a Q1 release? I think it was originally dated for some time in february but i think it was delayed. Anyone know if a new date has been mentioned for that?... Also I thought Crysis 2 was supposed to come out sooner than that? I guess it got pushed as well.
Dragon Age 2 then Bulletstorm. I'm so psyched for Dragon Age Ultimate Edition too- didn't get around to getting... uh... any of the DLC for the original so I'm going to pick that up and play through it all over again, haha. Bulletstorm's 'kill with skill' mechanic honestly looks really awesome.