Depends on who's doing the sequestering.
Scotch. But that's just because my answer to "Best drink" is also scotch.
If your job is affected and money will become tight, there's some cheap (<$20) but great scotch to be had, and if it isn't and think that things are just going into a slide, might as well grab the best drink you can! :D
Is this some kind of language barrier I'm not being able to break into?
Maybe. It's American political humor regarding current events. It's funny because Republicans took a shotgun to their face (without Cheney) and pulled the trigger, but lots of Americans got caught in the fire.
@winternet: If you aren't American then you might not get it. Basically our Congress couldn't agree on a proper deal in time for automatic spending cuts to take place. Republicans and Democrats refused to work towards a fair and balanced plan so naturally their antics have angered many.
Are you asking what the sequester is which is automatic spending cuts to government spending or why he would want a drink for the occasion? The drink could mean he might lose his job so he needs suggestions on how to get drunk or he wants to watch the spectacle.