I have heard a lot of good things about this game and was thinking of getting it. I heard that hard difficulty will have you sneaking around a lot and you will have less supplies. Would it be more fun to play on normal so that you can craft more things?
I've been playing on Hard and I've found as far as stealth games are concerned The Last of Us leaves a lot to be desired. However on the whole the most difficult time I've had so far was the first encounter with a clicker, everything else has been pretty much smooth sailing.
To more directly answer your question, there is a limit to how many of each material type and craftable you can carry, and playing on Hard I've never been in a situation where I didn't have something that I really needed (mainly med kits and shivs). The more interesting part in my opinion is you get fewer supplements--which are what you use for upgrades such as health and listen mode distance--so spending them is actually a meaningful decision.
@unilad: I just finished that part, tried it stealthily a couple times before deciding to just shoot everything from the entrance. For some reason the runners didn't all aggro me at once and I was able to pick them off one by one. Went through most of my ammo though.
@ericio123: Play it on Hard. That's what I did on my first playthrough and towards the end of the game I had one of the best experiences in gaming. People who played on Normal say that the game gets way too easier and you just mow down dudes.