S.T.A.L.K.E.R.

A Sci-Fi first person shooter series set in the area surrounding the Chernobyl accident site. S.T.A.L.K.E.R. stands for Scavenger, Trespasser, Adventurer, Loner, Killer, Explorer, Robber.

Sabrina, the Teenage Witch

Sacred

The Sacred series is a hack and slash RPG series reminicent of Diablo. You defeat enemies while at the same time collecting the loot that they drop, and earn XP to better your character.

SaGa

SaGa is a long running series of RPG video games known for its non-linear gameplay. The first SaGa game was released for the original GameBoy system in 1989 in the US as Final Fantasy Legend.

Sailor Moon

Pretty Guardian Sailor Moon, or simply Sailor Moon, is the massively popular magical girl series.

Saint Seiya

A series of video games based off Masami Kurumada's Saint Seiya anime and manga series.

Saints Row

The Saints Row games have traditionally been open-world, mission-based crime-themed games. The gameplay shares similarity to that of the Grand Theft Auto series.

Sakigake!! Otokojuku

This a comedy martial arts series that started as a manga in 1985 written by Akira Miyashita that takes place in a boys' private school with a really loud Principle.

Sakura Taisen

Sakura Taisen (a.k.a. Sakura Wars) is an iconic video game franchise first launched in 1996 for the Sega Saturn. Its core games combine strategy RPG elements with dating sim-style character interaction.

Salamander

Spin-off franchise from Gradius with but horizontal and vertical levels.

Sam & Max

Sam and Max is a series of comics, games, and television episodes created by Steve Purcell. It is known for its wacky and obscure humor.

Samantha Swift

Samba De Amigo

A series of maraca rhythm games developed by Sega.

Samorost

Samurai Deeper Kyo

Two video games based on the manga and anime

Samurai Jack

Video game tie-in with the animated series.

Samurai Shodown

Known as Samurai Spirits in Japan, Samurai Showdown is an SNK fighting game.

Samurai Shodown!

Samurai Shodown! Is a fighting game franchise consisting of 2 games for the Neo Geo Pocket and Neo Geo Pocket Color.

Samurai Warriors

Home of the Samurai Warriors (Sengoku Musou) games, the Japanese equivalent of Dynasty Warriors.

Sangokushi Taisen

A series of card-based real-time strategy games.

Sankyo Fever

Series of Pachinko video games. Released for the Super Famicom, PlayStation, Sega Saturn, and WonderSwan.

Sargon

Sargon is a chess game franchise for Personal Microcomputers.

Savage

The franchise that groups Savage and Savage 2: A Tortured Soul from S2 Games.

SAW

Saw is a franchise of videogame adaptations to the modern horror series.

SBK: Superbike World Championship

The official game franchise of the Superbike World Championship.

Scarface

A franchise of game adaptation from movie featuring the infamous Cuban drug lord Tony Montana.

Scene It?

"Scene It?" is a competitive movie trivia game based on a board game.

School Days

A franchise of visual novels known for their heavy use of anime cinematics. All games are developed by 0verflow

School Rumble

A series of games based on the anime/manga series of the same name.

Science Adventure

A Japanese sci-fi media franchise. It began as a series of visual novel games, co-developed by 5pb. and Nitroplus, and has since been adapted into other media, including anime, manga, audio drama, and film.

Scooby Doo

Games featuring Scooby Doo, the famous canine character from Hanna Barbera.

Scooby-Doo Case Files

Scooby-Doo Case Files is an educational point and click video game franchise by The Learning Company.

Scott Pilgrim

Series of Scott Pilgrim games.

SCP

Franchise comprised of two SCP games.

Scrabble

The Scrabble franchise is based on the popular board game of the same name.

Screamer

A series of Racing games by Virgin Interactive

Scribblenauts

A series of games by 5th Cell that involve summoning objects that all have different attributes to solve puzzles in creative ways.

SD Gundam

A series of games featuring "super-deformed" versions of the robots from the Gundam franchise. In some games, the robots are sentient (like the SD Gundam anime series), while in others the "SD" simply refers to the chosen artstyle.

SD Gundam G Generation

G Generation is a series of Gundam-related turn-based strategy games in which the player sends a variety of pilots and Mobile Suits into battle.

Seaman

Don't panic!

Secret Files

Secret Files adventure games.

Section 8

Battle in the distant future with this multiplayer shooter series.

SEGA AGES 2500

The Sega Ages 2500 series is a Japan-only line of budget-priced remakes for the PlayStation 2. In fact, the 2500 in the title indicates the cost of 2500 yen (about $25 US).

Sega Bass Fishing

Sega Bass Fishing, or Get Bass in Japan, is a series of arcade fishing games from Sega.