Yes, with a controller.
Stay with me here.
I have been perfecting my profile since beta weekend 2 and am excited to say that it works flawlessly. You can now play Guild Wars 2 as a third person action game, and honestly, it feels like it was designed to be played this way.
Yes, you can easily cast ground targeted spells. Yes, all of the controls fit on the controller. Yes, the ease of movement, casting, and attacking trumps anything you can do with a keyboard and mouse. Yes, it feels a bit like cheating.
As a note, this profile was created to replace the keyboard and mouse for combat only. Let's not be naive, the keyboard and mouse is still the way to go for menu navigation, inventory, etc, but for minute to minute gameplay you will never need to touch the keyboard and mouse.
See all my notes and grab my profile right here: