A few things to keep in mind:

• The release of Guild Wars 2 will not correspond in any way with the anniversary of GW1 (April 28). ArenaNet has said that they want the games to be independent of each other.
• Guild Wars 2 is currently in alpha-testing.
• Closed beta-testing for Guild Wars 2 will occur before the end of 2011.
• The possibility of open beta-testing will be explored as information is gained from the closed beta, and subsequently, the release will be determined by changes to be made after beta.
  

End of 2012 at the earliest, I'd say. I wouldn't be surprised, however, if it slipped way into 2013.

Q3 2012.

Q4 2011. I can't imagine waiting longer for this.Hell, I can't imagine having waitied, what was it, 5 years for this. Then again things only would've gotten hard once you got a good look at the game last year, which is when I started drooling over it.
 
Realistically, if all goes smoothly probably Q2 2012, or Q1 2012 if things go really smoothly. I remember hearing in a GC interview that what they're focusing on at this stage is putting in more content, which I guess could really mean there's lots more to do or little. 
 
I have a feeling that, since they're in alpha, they'll be announcing the final profession soon, and a release would probably be less than half a year away just because most things in the game would be out there and there wouldn't be much left to reveal at shows (which they seem to have been all into) other than a release date.

End of 2012 at the earliest, I'd say. I wouldn't be surprised, however, if it slipped way into 2013.

Jan - April 2012.

Either just before or just after Summer 2012. Definitely before the next WoW expansion hits sometime in late 2012. Otherwise it'll be early 2013. I don't want to wait that long.
 
I voted April-June 2012, thinking it will come out in early May. Late spring. I guess the optimal release window for them would be a couple of months after SW:TOR and before the next WoW expansion hits the market. I'm assuming SW:TOR will release in December 2011 and WoW in December 2012 - since high Summer is shit to release games, it has to be late Spring or early Fall. Of course GW2 would be even more awesome with an extra year of work put into it, but I'd really hate to wait until 2013 to sink my teeth into the game. Diablo 3 is another factor. Mayhaps Activision/Blizzard just keeps that one up their sleeves to try and steal GW2's thunder.
 
Closed Beta will happen around SW:TOR's release and there will be Open Preview Weekends in early 2012. The Preview Weekends for GW1 literally blew my mind way back when. I expected it to be better than WoW from all the fun I had with the story instances and the global PvP tournament (I was one of the first Warriors to learn 'Gash' from a mob and I dominated with Sever Artery and Gash for a night, until some Korean Monk got me figured out - I hated that every Warrior got that combo at release out of the gate), though finally it didn't hold up in comparison with World of Warcraft - lacking a persistent world. That's gonna change with GW2!

Q4 2011. I can't imagine waiting longer for this.Hell, I can't imagine having waitied, what was it, 5 years for this. Then again things only would've gotten hard once you got a good look at the game last year, which is when I started drooling over it.
 
Realistically, if all goes smoothly probably Q2 2012, or Q1 2012 if things go really smoothly. I remember hearing in a GC interview that what they're focusing on at this stage is putting in more content, which I guess could really mean there's lots more to do or little.   I have a feeling that, since they're in alpha, they'll be announcing the final profession soon, and a release would probably be less than half a year away just because most things in the game would be out there and there wouldn't be much left to reveal at shows (which they seem to have been all into) other than a release date.

From the interviews I have watched it seems there is still a lot of material/ideas that the team is discussing and playing around with.  Probably won't see an open beta until summer of next year and then even more tweaking will push it to late 2012.  They have shown that they want to make this game perfect and after all of the time they have taken already why not look at every single detail/issue from alpha and beta testing.
 
It will be a long road until release, but that just means an even better product.

Wow, I don't even see it possibly being out until it's done.

If it's any later than summer of 2012 I will lose my mind. I almost wish I didn't know about the game.

From the interviews I have watched it seems there is still a lot of material/ideas that the team is discussing and playing around with.  Probably won't see an open beta until summer of next year and then even more tweaking will push it to late 2012.  They have shown that they want to make this game perfect and after all of the time they have taken already why not look at every single detail/issue from alpha and beta testing.  It will be a long road until release, but that just means an even better product.

@RobbieMac said:

From the interviews I have watched it seems there is still a lot of material/ideas that the team is discussing and playing around with.  Probably won't see an open beta until summer of next year and then even more tweaking will push it to late 2012.  They have shown that they want to make this game perfect and after all of the time they have taken already why not look at every single detail/issue from alpha and beta testing.  It will be a long road until release, but that just means an even better product.

 It all depends on the Closed Beta which is scheduled for late 2011. Beta meaning the game's gonna be feature and content complete and the project's entering polish mode. Without a doubt they're shooting for a 2012 release window and I don't think they're going for Holiday 2012.

@Seppli said:

@RobbieMac said:

From the interviews I have watched it seems there is still a lot of material/ideas that the team is discussing and playing around with.  Probably won't see an open beta until summer of next year and then even more tweaking will push it to late 2012.  They have shown that they want to make this game perfect and after all of the time they have taken already why not look at every single detail/issue from alpha and beta testing.  It will be a long road until release, but that just means an even better product.

 It all depends on the Closed Beta which is scheduled for late 2011. Beta meaning the game's gonna be feature and content complete and the project's entering polish mode. Without a doubt they're shooting for a 2012 release window and I don't think they're going for Holiday 2012.

I agree with you in theory (and I did vote for Q2 2012), but I think we know what "polish" means to ArenaNet. They're willing to tear down animations, event chains, and even entire gameplay systems to build something stronger in their place.

I'm guessing Q3 2012. Spring or early summer could be a likely spot too, but I think they'll go for a later date than that. If it's not out before winter I get the feeling they'll just skip over the holiday season and wait til 2013.

@Dark_Lord_Spam said:

@Seppli said:

@RobbieMac said:

From the interviews I have watched it seems there is still a lot of material/ideas that the team is discussing and playing around with. Probably won't see an open beta until summer of next year and then even more tweaking will push it to late 2012. They have shown that they want to make this game perfect and after all of the time they have taken already why not look at every single detail/issue from alpha and beta testing. It will be a long road until release, but that just means an even better product.

It all depends on the Closed Beta which is scheduled for late 2011. Beta meaning the game's gonna be feature and content complete and the project's entering polish mode. Without a doubt they're shooting for a 2012 release window and I don't think they're going for Holiday 2012.

I agree with you in theory (and I did vote for Q2 2012), but I think we know what "polish" means to ArenaNet. They're willing to tear down animations, event chains, and even entire gameplay systems to build something stronger in their place.

Yeah, that's what scares me too. They really emphasize in the videos that I've seen that they really believe in the iterative process. Just because something is one way in this build doesn't mean it will be that way, or even be there at all, in the next build. Le sigh, tugging at my heart strings.

@Hugh_Jazz said:

End of 2012 at the earliest, I'd say. I wouldn't be surprised, however, if it slipped way into 2013.

Not sure if serious?