I've been tinkering with Infinite Space for some hours, as i picked it up today.  
 
The game is awesome! It looks like a Sid Meier's Pirates in space with stats and anime cutscenes. Has a generic plot of about a boy who wants to be a pirate, and other characters  just tag along with him for the ride.  
 
The difficulty is uneven with difficulty spikes from time to time, and the space combat is merciless as it doesn't give much to any room for error. But after learning the basic about combat everything starts getting into place for a great experience. The combats feel believable and convincing, giving an illusion inducing sensation.  
 
The game isn't as complex, as it can appear initially.   
 
It's highly recommended for anyone who can handle frustration and likes sci-fi scenarios, as it has the habit of presenting many times the Game over screen. 
 
If anyone has any question about the game, ask away.   
 
Gameplay Advice 
 

1. SAVE OFTEN! Even a small skirmish has a good chance to turn into a Game Over. 
2. Do small trips each time you set a course, as with each stop the stamina of the crew will decrease and if you are attacked, and the attack bar will take longer to replenish for your attacks.
3. Buy the blue prints if available in each station and upgrade your ship, with the devices created from them. 
4. Tinker with your crew, as each character on your team have strenghts and weaknesses that can enhance the strength of your fleet.
5. Play cautiously each battle. Even the starting enemies are tough, and with a bit of luck or not so much they'll take you to the starting screen. 
6. Use dodge often, as a barrage attack will take up most of your energy, and even if a normal attack - that are more accurate and do more damage when you're in dodge - hits it won't that much. 
7. Play attention to the color of the borders around the enemy ships avatars, as it gives indication of how replenished the action gauge of the enemy ship is. 
8. Dodge is particularly effective against Barrage and Special attacks, Normal attack is more effective when in Dodge, and Barrage hits hard when not in Dodge. 
9. Decide patiently, as just a series of enemy attacks can cripple your chances of a winning battle, and when attacking don't waste the green action gauge, as it will permit you to use dodge action after the attack to prevent a barrage attack. 

Hrm, i don't like game over screens much. I prefer just flowing from start to finish. I think I might be able to put that aside for Platinum Games though...

I'll be getting this soon, hopefully when I pick up a DSi XL next month.

Which chapter are you at?
 
Combat gets a bit tricky when fighters come to play though but my "pound the hell out of their weak ships first so that their barrage attack does little damage" still works quite well.

" Which chapter are you at?  Combat gets a bit tricky when fighters come to play though but my "pound the hell out of their weak ships first so that their barrage attack does little damage" still works quite well. "

Just how much space is Infinite Space?

" @Jeust: Chapter 3.... "

@ajamafalous

" Just how much space is Infinite Space? "

*sigh* It's like an emotional roller coaster as I read this thread.  One makes it sound impossible, the next says something awesome about the game.  I just can't figure out what to do!  I've been anticipating this game for months now, so I really want to go buy it today, but now I'm afraid it won't be fun until I'm 30 hours into it or something.  haha