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Lisa Trevor is an exclusive enemy to the GameCube version of Resident Evil. Her history is typical of the R.E universe in the way that it is filled with horrors of experimentation and lose of humanity. She is the daughter of George Trevor who designed the mansion, whilst her father is killed she and her mother are used as test subjects. In-game she is immortal and there is no way to beat her, the only option is to survive.

She has dreams of her mother and scattered around are letters of seeing her mothers face. Nurses have reported faces being pulled of that resembled Lisa's mother.

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