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Lizzie first appeared in the 1986 game, Rampage, and has since appeared in every Rampage game to date. In the series' previous games, she resembled a Godzilla-esque dinosaur, but in Rampage: Total Destruction, she grew shorter and has a more cartoony, exaggerated appearance. Her bio stated she was a scientist at Scumlabs and was somehow mutated along with George and Ralph into giant monsters.

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