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Carl "CJ" Johnson is the protagonist of Grand Theft Auto: San Andreas who, due to his mother's death, returns to San Andreas after spending five years in Liberty City.
Chris Redfield is a former member of R.P.D. S.T.A.R.s and a member of the global B.S.A.A. fighting Bio-Terrorism. Chris is one of the first and most recurring protagonists in the Resident Evil series.
Claire Redfield is the sister of S.T.A.R.S. Operative Chris Redfield. While initially only a young college biker, Claire quickly becomes instrumental in the fight against the Umbrella Corporation as a survivor of the Raccoon City disaster.
Playable Damage Hero in Overwatch. An American outlaw and former member of the Blackwatch strike team, later doling out justice on his own terms.
Lt. Simon "Ghost" Riley is the field subordinate of Task Force 141, an elite special forces group tasked with capturing Vladimir Makarov in Modern Warfare 2.
A female mercenary protagonist who stars in the game Fear Effect and its sequel Fear Effect 2: Retro Helix
Heather Mason is the protagonist from Silent Hill 3, and the reincarnation of Alessa Gillespie. She is given to Harry Mason at the end of the original Silent Hill.
The main protagonist of Nightshade.
The main protagonist of the 2002 3D Shinobi reboot. He also makes an appearance in Nightshade.
James Sunderland is the main character in the Konami video game Silent Hill 2. He comes to town searching for his wife.
The Orbital Frame which the player controls in the Zone of the Enders games. Piloted first by Leo, then by Dingo. This orbital frame is also the home of A.D.A, a detached back-up Battle A.I. which provides assistance to its current runner(pilot).
Jill Valentine is a former R.P.D. police officer and is now a member of the B.S.A.A. fighting Bio-Terrorism around the world. She is a staple of the series.
John Marston is the lead protagonist of Red Dead Redemption. His primary goal is to track down and kill the remaining members of his former outlaw gang so that he may be reunited with his family.
Undercover detective & getaway driver who appears as the main protagonist of the Driver series.
Leon Kennedy was an R.P.D. officer who survived the Raccoon City outbreak. He is now a skilled government agent tasked with the extermination of biological weapons created by the Umbrella Corporation.
Link is the iconic protagonist of The Legend of Zelda franchise.
Luis is the personal bodyguard of Tony Prince, bouncer of Maisonette 9 and Hercules, and the protagonist of Grand Theft Auto IV: The Ballad of Gay Tony.
One of the main characters of Silent Hill 2, Maria helps James navigate through the twisted town of Silent Hill. She closely resembles his dead wife.
The anti-hero protagonist from GTAIV, Niko is of Serbo-Croatian ethnicity, and an army veteran of the civil strife of the Balkans during the early to mid 90's. He finds himself quickly disillusioned by the fallacy of the "American Dream" after emigrating from the former Yugoslavia to Liberty City.
Razputin (Raz for short) is the protagonist of the game Psychonauts. He ran away from the circus in an attempt to join a camp full of psychic warriors in training.
Samus Aran is the protagonist of the Metroid series. As a bounty hunter, she uses her armored power suit to hunt space pirates and other dangerous forces. She frequently crosses paths with dangerous creatures called Metroids in her adventures.
Terra is a character in the Kingdom Hearts universe who eventually becomes Xehanort's vessel.
Professional getaway driver who is arrested and returns as a ex-convict on a quest for revenge.
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