... my guy keeps jumping out of cover. I don't know what the fuck is going on with my fingers. I have beaten the game 2 times on Hard and it NEVER happened. Now I'm on Insanity and 90% of my deaths are caused by me jumping over whatever cover I'm using. It is driving me insane. I'm in the collector ship right now, at the part where everyone seems to think is the hardest in the game. I have died 5 times, all 4 of them because I jumped out of cover. 
 
Am I the only one to whom this happens?

I had an issue where the camera would get stuck in a sidescroller Contra angle, which made it near impossible to navigate and it only happened in the middle of firefights.
 
Also, there are attacks that one of the creatures on the ship does that will knock you out of cover.  You're not getting hit by those are you?

If I remember right the collectors have an attack that can knock you out of cover. Given that you've beaten the game twice you are probably aware if this, but just in case you're not, is that possibly what's happening? If not, I have no idea. I beat that game three times and never had that problem.

" You're not getting hit by those are you? "

Heh. That will do it. Hope you manage your way through isane, it can be a bitch in spots because of random little things like that.

Insanity really highlights the less than great combat in that game. Some parts were truly frustrating because of small things like this.

I got it. I died 7 times on that part. Now I'm done with the collector ship. I hear the next hard part is the IFF thingy with all those Husks coming at you. Any tips before I get there?

All kinds of weird shit happened to me when I played ME2 on Insanity. Got stuck behind cover and couldn't move, climbed on top of cover, went through the roof several times and got stuck in random level geometry. This ain't no Gears of War, that's for sure. I don't have any good advice on strategies, just max out ammo types and adrenaline. I hope you picked up the assault rifle on the collector's ship, because you'll be using it a lot.

Horizon and to a much lesser extent the Collector ship were the two biggest humps to get over on my insanity run although I was playing as an Adept so it really depends what class you are. Playing on insane really shows you how average and shitty parts of the shooting are in this game. Some things I found frustrating to watch were Shepard getting stuck on cover, randomly exiting cover while moving along cover, going into that stupid 5 second "I am on fire" animation which allows everyone to shoot him, have the camera get be in awkward places, have your team mates do stupid shit like walk in front of you or go on some long round about route to get to the cover you told them to get to, glitching into walls and getting stuck on top of crates and cover, not being able to exit a mission when it was finished and the movement while in combat was stiff and slow meaning it takes way too long for you to turn around and face enemies. Great game and some of these problems only really become problems on the higher difficulties but they should not be problems at all. I hope since they already went full third person shooter in this game that they get people who can actually make a decent third person shooter for the next game.    

" I hope you picked up the assault rifle on the collector's ship, because you'll be using it a lot. "

" @xyzygy: Soldier. So far it has proved very useful. "

" If I remember right the collectors have an attack that can knock you out of cover. Given that you've beaten the game twice you are probably aware if this, but just in case you're not, is that possibly what's happening? If not, I have no idea. I beat that game three times and never had that problem. "

I had a controller with a janky left stick.  When ever I would use the pause-select power in cover Shepard would always creep left in cover after I exited the menu.  The stick didn't recenter properly and I was usually selecting a power on the left side.  Sometimes he would get confused at the edge of cover and get killed.  Pretty annoying. 
 
I'm a fan of melee and shotguns on husks.  Bring Grunt along and let him charge around too.

The biggest problem for me with Insanity aside from it is incredibly cheap in parts is the game is too difficult for its own mechanics. The game is too reliant on cover on Insane but without any forgiveness on the fact the cover mechanic is very rigid and can be hard to go into because weird instances of animation priority where Shep has to be facing a certain way in relation to whatever it is you want to stick to in addition to not being in the middle of another action. I died probably dozens of times over my near 40 hour playthrough because of stuff like I was running to a crate but was slightly cockeyed and that moment of awkwardness let them hit me with that knockback attack I never saw in other difficulties and 3 dudes shot me.  Just thinking of insane pisses me off and makes me hope there isn't a trophy/achievement in ME3 again for it.

" @AuthenticM said:

" @xyzygy: Soldier. So far it has proved very useful. "

OK, I can't really help you much there because I stayed as far away from that class as possible :P  Also... if you think it's hard on Insanity with a Soldier... try it with an Adept like I did :| "

" @AuthenticM: 
DING DONG!   "Welcome to the wonderful world of ME2 on insanity where all the game's faults become clearly visible. Please take a number from the counter and step forward when your number is called"  "

I only had one problem. It was only on the 360 version, but the problem was that every time I was on cover and wanted to stick to the right, or just be stationary, Shepard often moved gradually to the left as if my controller was messed up, but I know it isn't.

" @AuthenticM: 
DING DONG!   "Welcome to the wonderful world of ME2 on insanity where all the game's faults become clearly visible. Please take a number from the counter and step forward when your number is called"  "

Yeah, insanity definitely brings out the flaws in the game. Mostly AI issues (teammates getting stuck on something and dying). Lots of accidental leaping from cover because you hammered the A button (or whatever the cover button is on your controller of choice) one too many times in an attempt to make sure your character actually ducked behind cover,  because sometimes Shepard just decides standing right next to cover and getting shot repeatedly is what you meant to do when you hammered the A button.