I have yet to go and get Tali and Samara, but so far I've been rollin with Garrus full time, he is the best character in that entire game. And also Thane, i only got him recently but i use almost exclusively now. If theres a third it would be Mordin, his powers are amazing, especially Neural Shock. Godammit i love this game. What about you guys?

SPOILERS MAN ALKJDSLKJALKJSFD, WATCH IT. 
 
I roll with  SPOILER WARNING: Click here to reveal hidden content. 
 
Wtf, broken spoiler thing, but I roll with G-man and Sub Zero.

I like to switch around. That's the good thing about equipment in this game--there's no penalty for trying to use everybody. But Thane and Mordin are my personal favorites, so they're in my squad pretty often.

Havnt played Mass Effect 2 yet, but I always rolled with Wrex and Garrus in the first one.

Garrus is almost always a member in my party. His party armor-piercing rounds is so powerful, especially later on. The third person varies depending on what I need.

I went with Legion and Samara. Legion was useful with his tech skills and sniping and Samara was my biotic choice.

I mixed it up so that I rolled with everyone about equally, with the least time spent with Mordin and Legion, Mordin because his abilties were so weak against shielded enemies and Legion just because he shows up so damned late in the game. 

I've actually used Miranda and Jacob a lot I also use Garrus a lot most recently I have been using Grunt and Mordin because I was doing their loyalties. They seem like a good team I might continue to use them.

Using Grunt quite a lot at the moment as he complements my skills quite nicely, but I have been trying to rotate quite a bit + if someone has a personal reason for being somewhere I tend to bring them along for the whole ride, rather than just their mission (which they have to be in your party for)

I change it up depending on what the mission is.  I kinda like to role-play in the way of whom would actually probably be on the mission at hand.

Garrus and Miranda.  I'll sometimes switch out Garrus for Jacob.

Depends on the enemies in the mission. If it's Geth or Mechs then I go with Tali/Legion and Jack, Humans then I Thane and Grunt.

I switch around a fair bit... but I've surprisingly been using Zaeed alot... his grenades are awesome!

I switch it up for each mission. One of the many great things about this game, it doesn't punish you for messing around with multiple characters.

Garrus and Jacob. Sometimes Garrus and the Doc. Garrus has my back.

Garrus and Jacob. Sometimes Garrus and the Doc. Garrus has my back.

As an adept on insanity I roll with Mordin at all times (wide incinerate is just too valuable against husks and large groups of krogans) and either Miranda or Zaeed.

"

I change it up depending on what the mission is.  I kinda like to role-play in the way of whom would actually probably be on the mission at hand.

"

If it's a low-impact mission, by which I mean anything not on Insanity, I like to use Tali and Legion. Doubled drones break up enemy groups a lot to take out with my inferno rounds on machine gun or sniper rifle, with Adrenaline. When either one isn't available, Jack is the next in line, because of shockwave.

" @creamypies: I like Zaeed a lot, both his voice acting and he does well as a fighter, too.  But they just don't develop him quite enough for me to feel right using him instead of the other characters... "

Garrus and Tali were my go-to team.  Garrus because he rolled with me consistently throughout Mass Effect 1 and Tali because I'm old school.

Guess I need to start by saying I am using the Solider class.  Haven't got the last party member yet so I've been using Grunt for extra muscle and Samara for the Biotics.  In addition I added Slam to my Solider by completing a loyalty mission.  Burn through enemy shields and have Samara use Pull followed by you using Slam and they're done.

I go with Jack all the time. I upped her bio powers like mad and her shockwave ability is really good. Looking for a good tech character now. I pissed Miranda off so she's out now but I haven't gotten Samara or Legion yet. Thane is my current stand-in.

I like to swap around a bit, but Garrus is a definite mainstay. I've been using Miranda more ever since she started going all "ho" on Shepard.  
I also roll regularly with Grunt and Tali. 

Mostly Garrus and Thane, sometimes Garrus and Tali.

Depends on the situation. For battles involving mechs, I bring Tali and Garrus. For fights involving squishy mercs, I like to have Zaeed and Mordin. If I'm fighting Collectors, Thane and Garrus for their ammo buffs.

Jacob and Miranda. Humans FTW.

Mordin and Grunt all the way. I never have problem with them dying, and Grunt's humorous comments make the missions even more enjoyable.

ZAEED! my dude too bad they half assed zaeeds dialogue and grunt/mordin are my favorites but i take everyone out a little

I try to use everyone all the time. But many get the shaft.

garrus and miranda

I roll with Grunt and Jack. Jack's shockwave abilities can hit a lot of different enemies for mucho damage, and Grunt has a lot of useful ammo types, as well as his football charge attack, plus his specialty in assault rifles and shotguns. 

Jacob And Garrus, Sometimes i bring Zaeed. But I'm just starting on the 2nd part of dossiers, so it will properly change.

I was using Garrus and Miranda for a while, but recently I've replaced Miranda with Thane. 

I usaully switch people out depending on the mission, though I really like having Tali or Legion along so that I can run a drone as a temporary distraction. 
 
I also run Garrus a lot because of his Armor Piercing rounds and Overload. 
 
Also Grunt. Because he is Grunt.

Miranda and Grunt. We were like a couple walking the dog at the park.

Garrus is always a stalwart on my team. He's the most engaging character, and he's sort of like an old friend at this point. 
 
After that, it's a crapshoot between Miranda, Jacob, and Thane. Thane and Garrus have some good banter, so I like to have them together, plus Thane's biotics offset Garrus's assault-based powers.

Playing Insanity, you have to decide who you take for each mission. So it's always changing as of right now. But on my first playthrough, I used Legion whenever I could and switched up between Garrus and Thane.

I change it up depending on the mission. But my defaults were Miranda and Tali I love me some space blouse.

Garrus and Mordin if i don't care about performance.
 
If i do, it depends on class, but usually Miranda (squad weapon damage, good array of powers) and...someone else.

I'm kinda on the fence on this one. I almost always choose Tali, because she's my fav character and garrus, because he's a cool dude. I used Tali and Wrex in the first one, and might use Grunt and Tali for a while. Using Grunt is like having a really cool pet imo. I like pets.

I run and occasionally walk, sometimes even chat to, but never roll with: Miranda and Zaeed, but that's all I have at this moment, just got Archangel.

Legion and Tali or Thane and Garrus. Tends to change if I'm in combat or just going around the Citadel and such. 

Garrus and Thane, always.

depends on enemies. if there robots I'll bring Tali or Legion with me for example.

Leigon, Thane, Garrus and Miranda. I switch it up a lot, so I really use everyone.