So, mixed impressions.
The opening sequence, especially played at a high res (my native is 1920x1080) looks genuinely awful in places (be sure to zoom in on the 'fleeing civilians'). Super low res textures and the animations are really stiff. Random NPCs still haven't received the same attention to the faces as the main crew and seem unnatural and plastic-y as a result. Combat feels clunky, although movement is much improved generally over 2. Guns feel better to shoot but it's still no Gears.
Also, no gamepad support. This is definitely NOT a game where you want to be up close to the monitor considering the quality of some textures. Can't remember if ME2 had this or not though.
Second level in the demo is vastly superior, both visually and mechanically. Main characters look amazing (although facial animation is still very stiff) and the lighting has clearly seen some upgrades. Also goes some way to actually convince me that the combat is more than playable. Enemies still take too many hits to go down but it plays well. Stupid universal cooldown is still in effect which I've always taken issue with. Limits tactical play and seems like an easy cop-out to not have to balance all the powers well so they're not game breaking when used in tandem.
What do you guys think?
EDIT: I also started playing the multiplayer recently and it's probably the best take on Horde Mode I've seen in the past few years. Seriously, I'm shocked. And completely addicted. The levelling/progression system is ripped straight out of the singleplayer so it feels every bit as in depth, the graphics look better than the campaign, the maps are well designed, the classes varied, the enemy waves have a great balance and, overall, it's stupid fun. Was not expecting that. At. All.