I love the controversy around this trailer, that shows Kojima hitting the pulse of the current times with some of these topics.
But that trailer is maybe a little bit too spoilerish to me, with all those cast introductions going on or seeing that snake gets an decent robo arm/leg as replacement. Especially after that rather disturbing reveal trailer that's maybe a little bit too much "reveal". I rather don't know stuff like that in advance, as to dive into the game without as little knowledge as possible.
You will have forgotten everything by the time the game comes out and you can bet it's gonna all be some big ol' chaotic mess again anyway. It's a Metal Gear game after all ;)
That said, now I desperately NEED to hear Snake at some point yell "We're running out of time!!!"