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Vulture is a villain in Marvel Comic's Spider-Man Series. Adrian Toomes created the flight suit and became the Vulture.
Rhino is a nemesis of Spider-Man. His costume gives him superhuman durability and strength.
Spider-Man villain often associated with Spider-Slayers, along with his father, Spencer Smythe.
The Chameleon is actually one of Spider-man's earliest super-villains. A master impersonator, he uses his costumes for villainy and fun.
Eddie Brock is a character in the Marvel Universe best known as Venom. He became Venom when he joined with an alien symbiote life form and was one of the most fearsome enemies of Spider-Man. He has also use the Anti-Venom and Toxin symbiotes at different points in his life.
The Sandman, also known as Flint Marko or William Baker, is a Marvel Comics character and a regular enemy of Spider-Man. He has occasionally been a superhero, and even briefly was a reserve member of the Avengers.
The editor-in-chief of the Daily Bugle in Spider-Man games. Has an agenda against the wall-crawler. He is portrayed by J.K. Simmons in the Sam Raimi Spider-Man Trilogy and the Marvel Cinematic Universe.
The Kingpin, aka Wilson Fisk, is the biggest crime lord in New York City, and possibly the world. He operates under the guise of a legitimate businessman and philanthropist, much to the chagrin of Spider-Man, Daredevil, and the Punisher.
Scorpion is a nemesis of Spider-Man. He was once private investigator Mac Gargan, until J. Jonah Jameson hired him to be the subject of an experiment that gave him immense strength, a costume with a tail that fires lasers, and the deep-down crazies. He was the third Venom.
Doctor Otto Octavius was a scientist who turned to a life of crime, using a set of four flexible mechanical arms originally designed to assist in scientific research and labwork to give himself a major advantage over the police.
With a terrible track record, a costume resembling a soiled mattress, and a name that inspires fear for all the wrong reasons, the Shocker is primarily a laughingstock. This Spider-Man villain has gauntlets that allow him to generate powerful shockwaves.
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