There are A LOT of shooters out there, and for me finding the perfect weapon is always fun. I'm talking about that one weapon that destroys anything and everything and when it's a pistol it's even sweeter. If you could make a page here on Giantbomb for "overpowered handguns" what would you add? Other than the random pistols available in Borderlands that do 900+ damage, I've got a couple I would put on there:
Halo CE Magnum
The very first gun you get and whenever that weapon was available I would immediately pick it up regardless of the situation. It has extremely powerful rounds and zoom capabilities that allow long range combat. Not to mention killing Hunters with one shot to the back....talk about overpowered!!
The sequels never did justice to it. Halo ODST had a similarly overpowered pistol but by then it just wasn't the same.
Call Of Duty 4: Modern Warfare Desert Eagle
I've played a lot of S&D and watched a lot of people playing while I was dead (I died a lot). There is always one weapon that people switch to when in a life or death situation. It takes 1 to 2 shots to down anyone, I've seen people go one on one with a Desert Eagle against an AK and come out on top hundreds of times. Thankfully unlocking it takes some time but if you're patient enough you'll get an awesome gold DE....and everybody loves gold.
Dead Space Plasma Cutter
Again, the first weapon you get in game, it's Halo all over again. Thankfully the cutter remained as bad-ass in the sequel. It's no wonder there's an achievement for playing the whole game using only the Plasma cutter. It's one of the best weapons for dismembering space monsters and shooting it is just plain fun!