Inspired by this thread.

Naturally, the game would be called Super Smash Sisters, named after the Giana Sisters :P

Also there would be:

• Gordon Freeman
• Guybrush
• Commander Keen
• Jazz Jackrabbit
• Morte
• Steve
• Isaac

Who else should be on the list?

Sarah Kerrigan

A Cessna 172

Geralt, Max, Agent 47, and this guy:

The main guy from Crysis, the devil from Diablo, Max Payne, CT from counterstrike, and various TF2 characters. I know that all of these characters have made appearances on a console at some point, but they are primarily PC games.

Purple Tentical

Doomguy and Cacodemon

• Duke
• Cyberdemon
• Cain or Tyrael
• Lara Croft
• Leisure Suit Larry
• Ben (Full Throttle)
• Manuel Calavera
• Illidan
• and just a floating AWP

Crysis guy, Doom guy, Deus Ex guy, Battlefield guy and some Warcraft guy. 
 
A lot of guys simply.

@AhmadMetallic said:

Geralt, Max, Agent 47, and this guy:

Oh man, where have I see that guy before?

Manny Calavera

I'd never play as anyone else.

@aceofspudz said:

@AhmadMetallic said:

Geralt, Max, Agent 47, and this guy:

Oh man, where have I see that guy before?

90% sure it's Battlefield 2

Cate Archer

Kane (from C&C series)

A female Blood Elf...because, you know.

A throng of Skeletons, Serious Sam and Gandhi.

B.J. Blazkowicz?

DooM Guy, Duke Nukem, The Heavy and  Serious Sam. 

Captin Price from COD 1. Not the modern warfare guy.

The smiley from Minesweeper and the Yeti from Ski Free

My ultimate list of characters:

Benevolent Cow from Black & White

Kilrathi pilot Hobbes from Wing Commander 3

Karate guy from Karateka (the original)

Kyle Katarn from Jedi Knight - Dark Forces 2

Sectoid from original X-Com

Manny Calavera from Grim Fandango

Purple Tentacle from Day Of The Tentacle

Gordon Freeman from youknowwhatgame

Kane from Command & Conquer

Three-headed version of Bernard, Laverne and Hoagie from Day of the Tentacle

Duke from Duke Nukem 3D

a Sim from The Sims

Cacodemon from Doom

Abe from Oddworld

Edward Carnby from Alone In The Dark (the original)

Zerg Hydralisk from Starcraft

The boss you fight at the end of the single player is Bill Gates throwing BSoDs at you.

• Sam & Max
• Gordon Freeman
• Minecraft Steve
• Geralt The Witcher
• Duke Nukem
• Wolfenstien dude (cant remember his name)
• Agent 47
• Larry Laffer
• Linx Penguin

@pandorasbox said:

the devil from Diablo

You mean Diablo? :)

@aceofspudz: Kerrigan, Evil Kerrigan, and revived not as evil but not quite not evil Kerrigan (yes that's as stupid as it sounds)! 3 Kerrigans for the price of one.

Trying to think about some obscure ones.

Mothership from Homeworld

STALKER from STALKER

The boobs from Trespasser

Spehs Marens from 40K

A tractor.

@Andorski said:

The boss you fight at the end of the single player is Bill Gates throwing BSoDs at you.

No. It's a moral choice system where you have to choose between the working and efficient but gameless and overpriced Steve Jobs and the full of games but buggy, virus-ridden and problematic Bill Gates.

Or you can go down the middle and pick the more neutral Linux.

Clippy should be the joke character.

Super Meat Boy.

Janitor Guy from Dustforce.

Mr. Twig Mr Lantern Mr Poppy Head Mrs. Mushroom & Mr. Feather.

Terraria Guy.

Father-Mother.

Capt. Viridian.

Tiny.

Steve.

Daniel.

Hotline Miami Guy.

A Troll.

I don't even like fighting games but the Roster for a PC focused game would be so god dam Huge! Makes me sad that it will never happen.

The rapist from RapeLay?

It should have Mod support, so I guess anything.

Thrall

Alma

Meat Boy

The kid

Guy Thrushbrush, Grim Fandango

No one because there is no such thing as a "first party" game on PC. Either that or copy/paste whatever is in the Xbox thread and make it exclusive to Windows machines.

Random solitaire card?

@laserbolts said:

Random solitaire card?

OH GOD YES. What about that adware purple monkey.

A truck.

Paul Allen.

@Fredchuckdave said:

@aceofspudz: Kerrigan, Evil Kerrigan, and revived not as evil but not quite not evil Kerrigan (yes that's as stupid as it sounds)! 3 Kerrigans for the price of one.

And all three take up their own character slots on the menu.

• Cate Archer
• Max Payne
• Geralt of Rivia
• Larry Laffer
• Bill (Left 4 Dead)
• Gandhi (from civ-games)
• Doom Marine
• B.J. Blazkowicz
• 4D-boxer
• King Graham
• Laura Bow
• Lara Croft
• Shodan

Duke Nukem

Slender just for shits and giggles.