1. BioShock Infinite
Bioshock is one of my favourite games; I'm glad to see an actual Ken Levine 'sequel' to the original. Hopefully the story will throw a few curve balls; at the moment, I'm sensing that the game will take some familiar turns.
2. Quantum Conundrum
Looks like Portal 1, but with more fluffiness :D I'm actually really excited to see another Kim Swift puzzle game.
3. Far Cry 3
I really loved Far Cry 2; hopefully this takes what was great about 2 and work on ironing out some of its issues.
4. Borderlands 2
I was never really expecting a sequel to the original, but sure, I'm not complaining; I could always do with some more Borderlands...
If Dead Space was a point and click adventure...
Looks adorable; hopefully it will be as good, if not, better than Machinarium.
7. The Witness
Hopefully this will end up as another well designed/clever/thought provoking puzzler, just like Braid was. I can't wait to check it out.
8. Professor Layton and the Miracle Mask
The Layton series is great, but things are definitely getting stagnant; hopefully Layton on the 3DS will revitalise the series a bit.
9. Prey 2
Even though it will be vastly different from the original, it still seems like it has the potential to be a great non-linear shooter.
10. Tomb Raider
I've never really cared about any of the Tomb Raider games, but this fresh start seems like it holds a lot of promise.