HoN really is an exciting, challenging game. Once you get past the community ( I recommend staying in the No Stat games for awhile as they are a lot more laid back) the game really opens up to a great multiplayer experience. I haven't gotten around to trying LoL yet but I hear its a lot more relaxed. I already payed for HoN so I'm gonna stick with that anyway.
Borderlands will ruin friendships if you play with the wrong people, so much looting. Single player was still good for me, but I was never really motivated to buy the expansions. I would recommend it though
Yeah, going to RIT's Game Design and Development program right now. The program is challenging and requires three quarters/summers worth of internship/work with a company in the field in order to graduate. As far as I know people from the program have been employed at Valve. Microsoft Studios, Volition, Vicarious, and EA.