From what I can tell, the whole "anime avatar" thing is just an observation that turned into a running joke. Obviously not everyone that is into anime is an asshole, but you can't deny that a lot of assholes are into anime.
I watched Kill La Kill recently. The costume design did make me feel a little uncomfortable at times, but the animation/art and humor is top notch.
Even if it is a joke which, in many cases its not its a very poor joke when you're a person like Leigh Alexander on Ben Kuchera who regularly campaign for equality for Women and Minorites in gaming. If that's going to be your platform while at the same time you shun entire groups of people because of an interest they share well then I can't very well take anything you say seriously can I?