I think it looks cool, San Andreas was probably my favorite GTA game, but the one thing that always bothered me about it, was that the game world never felt distinctly like LA. From what we've seen in the trailer I think Rockstar nailed it. I'm looking forward to seeing more of the game and getting to know the protagonist.
Oddly enough, this news has sort of dampened my interest in DMC, since I really was only looking for hints of how the studio has grown since developing Enslaved. The combat was the weakest part of the game and following DMC I imagine they could have very successfully revamped the combat for a sequel.
I still plan on supporting Ninja Theory moving forward and will buy DMC when it comes out. I'd advise anyone who's played Enslaved: OTTW and enjoyed it to also check out the DLC 'Pigsy's Perfect 10'. Who knows, with enough fan support perhaps the team can create another original title the likes of—Enslaved: OTTW, that is every bit as fun and engaging.
If they can nix any future morality systems and tell a straight up focused narrative I think Sucker Punch can make a truly great game the likes of Uncharted. I'm really looking forward to it, we probably won't see it till PS4 though.