The hammiest and best Videogame villain. Second only to Robo-Hitler in the Villain stakes, but as a character, you can't beat good old Kane. The best Psychopathic slaphead immortal megalomaniac ever.
Need I say anything?
3. John Marston
What you think of him probably depends on how you play the game, but if you play the game as I did, honourably and kindly, he appears to be an outlaw trying to escape his past, and do his best for his family, the past however, shall never release him. Blessed are the peacemakers.
4. Psycho Mantis
A very cool Villain, and surely one of the best names for any villain ever?
Whether a villain or neutral, he's very cool, he's mysterious, and he's awesome as hell.
6. Thane Krios
An honorable and fearless assassin. A very cool and sympathetic character. My favourite member of your ME2 team.
7. Solid Snake
The coolest game character ever. What he lacks in depth he more than makes up for in awesomeness and style.
8. Manny Calavera
The best Adventure game character ever. Could eat Guybrush Threepwood for Breakfast, and could then take his soul to the afterlife.