I just hope that they don't get stubborn like with Call of Duty and Treyarch, where they would see the cool/better mechanics added in one game, but then take them out of the next game because 'we want to do it our way.' New Vegas didn't have the same ambiance and feel that FO3 did, but mechanically, the way they handled stats and speech checks in New Vegas was so much better. In FO3 you could have super low Speech skill, have a 5% chance for a speech check to work, and just save/reload/try it again 25 in a row until to randomly worked. In NV it just plainly told you, nah you need 75 speech for this, you need 7 INT for this, ect. It made putting points into barter and speech feel meaningful in NV.
I think, from how they handled stats and speech in Skyrim, that they're probably learnt their lesson. But you never know.