Pros:
Technically impressive graphics
Artistically solid
Appropriate musical score
Amazing sound design
Satisfying combat
Constant sense of dread/tension aka good pacing
Zero-G environments work well
Cons:
Poor Close Quarter combat
'Cheap deaths' = no fun
Strange weapon balance (flamethrower = teh suck, plasma cutter = godlike)
Story while interesting is nothing to write home about / lots of potential not really realized
issac needs more movement options (A quick side step or roll would be fantastic)
Why not have a hotkey for stasis too? Aka in-game inventory management can lead to some incredibly frustrating situations.