Future Assassins of the Past
Playing some AC III, I've noticed Desmond must be just about out of ancestors to call on for precursor knowledge. Might be time to retire the face-morphing Northie candidate for some fresh blood. Seeing how there's probably still a whole mess of Assassins out there with centuries of history they can tap into, it creates a whole host of possibilities.
Now, some of these suggestions for possible Assassin's Creed settings might skirt the edge of credibility, given even the series' already tenuous grasp on historical accuracy, but I was just given a recap tutorial on AC 2's notoriety system by Sam frickin' Adams so as far as I'm concerned the series has already air-assassinated the shark in that respect.