@mlarrabee: Oh I don't know about that at all. Plenty of people in here who are obviously insulted by being called "10yrs old" for enjoying the humor in much the same way anyone who enjoys or can tolerate fanservicy Japanese games are met with "Well I'm not 14yrs old anymore".
That's probably very true. Taste affects perspective, and things we enjoy often get a free pass on the same content for which we condemn other things we don't enjoy.
Personally, I don't enjoy most Japanese storytelling in games because it's overblown and it doesn't know it. South Park has known since season four. The knowing is the key. But even meta-humor is very touchy because poking and prodding an audience is just as insufferable to me as being bombastic without any irony. Matt and Trey have fallen into that hole of nudging and winking to their viewers more than a few times. I find most funny the humor that goes over most people's heads. This isn't because it makes me part of an elite that "got that joke," but because it's pointed and quiet enough that most don't hear it. There are plenty of South Park jokes about Christianity that I find really funny as a Christian. But I know there are a ton that go right over my head since I haven't an "outsider's" perspective, and I'm glad that those jokes, too pointed and quiet for me, exist for others.
@hailinel: I guess I didn't think I'd have to spell it out! My above post gives a bit more insight into my opinion, but here's the short answer: South Park knows when it's being dumb, and Metal Gear Solid doesn't.