Sadly I'm one of the (seemingly few) people that LOVED AC3 and Ratohnhaké:ton as a character. I loved the wilderness and climbing in 1700's Boston. I loved hunting animals and climbing trees and cliff sides. Spent hours exploring the wilds and wanted more.
I would love to see more of this setting, its unique and interesting. Japan or China would be really boring. Maybe take it to Central/South America? Aztecs or Inca. BEFORE any Europeans came.