Depression Quest was not at all what I was expecting. I guess I'm glad I played it before reading this, because I probably would have written it off entirely had I known it was, and I'm boiling it down, a choose your own adventure story.
As empathy-inducing games go, I felt ambivalent about Depression Quest. Parts of it hit very close to home, while others felt like a charicature of a depressed person. I suppose that makes sense from both a story telling perspective and a design constraint, but it took me out of the experience a bit.