This year alone I have 7 games that I am following.
Far Cry 3: Mainly for single player but I think the story looks awesome. The villain is probably the best villain in recent memory.
Resident Evil 6: I have beat every main RE to date and I feel obligated to get RE6.
Assassin's Creed 3: I have never been interested in AC before but this one has me hooked with the setting.
Need for Speed: Most Wanted: Best looking racing/driving game I've seen.
Halo 4: It doesn't look like Halo but it's still amazing.
Black Ops 2: More of the same but I really loved wager matches and this one has a zombie story mode?
Hitman: Absolution: The Original Assassin