Shenmue I and II. I would do anything to just get an HD overhaul of these games, only to show the series some support and eventually, maybe, if miracles do happen, get another sequel.
Tombi! Who wouldn't want to wrestle pigs in glorious HD?
I would also like to see a real remake of Yakuza 1 and 2 using the Yakuza 5 engine. I'd love to replay both but all the loading times between battles and the fixed camera perspective while exploring the city is rough.
But even if that was to happen i doubt SEGA would even consider translating it.