I'm leaning towards a pure physical build like I usually play my first time through. It seems like STR has by far the best raw damage if you're going pure physical, but I just didn't like the moveset of any of the pure str weapons. However, considering you pretty much need a blunt weapon to get the upper hand in some situations, I do tote a club around.
Anywho, here's my preferences atm (numbers are quoted at my current stats of 40str, 20 dex - I'm aiming for a 40/40 quality build);
- Claymore +10: My favourite and hardest hitting weapon at the moment with 380 attack (290 base, 90 from the C/C scaling). That number itself isn't all that impressive, but coupled with the thing's amazing reach, speed and moveset (slashes on the R1s, thrust/slash combo on the R2s) , this will likely end up on many "best weapons of Dark Souls 2" lists much like the original did in DS1. It doesn't use TOO much endurance either - I can chain 5 hits with my 132 stamina and still have room to roll.
- Sun Sword +10: I actually expected this to be my jam in DS2 as coming from an Uchigatana backaground in the original DS, I wanted something with very fast slashing R1s and thrusts on the R2s. Oddly enough, though, I used the Claymore and Drangleic sword on the lead up to getting this and ended up preferring their reach and movesets. That said, this weapon is certainly no slouch. Perhaps its biggest strength is the high damage from A/A scaling (roughly 330 for me - 175 + 145ish) coupled with using very little stamina. I can chain 6 or so hits with this thing in some instances, and still have enough stamina to do a roll.
- Club +10: This thing has a pretty average moveset (slashing motion... and a heavier slashing motion - neither with much arc or reach), however it hits like a truck. With S strength scaling it is as fast as my sun sword, uses just as little stamina but is sitting at 350 attack (210 + 140). Considering it does strike damage, this thing can straight up massacre some foes.
On my offhand I tote the Drangleic shield - it's a nice, balanced shield imo - and a bow of some form depending on my mood.