The one time I beat FTL (on easy, mind) I got incredibly lucky with weapon drops. Judicious use of the anti-bio beam made it so that I didn't need a teleporter, so I could get max scrap without risking my crew as long as I could defend my ship decently. (I used the basic Kestrel, for the record.) Against the Rebel Flagship I had a combo of a Heavy Laser, Burst Laser and an ion beam or the anti-bio beam where necessary. Also, again, tons of luck, because there were several points where I teetered on the edge and probably would have lost if I were playing on normal. That'll probably be the only time I beat it, haha. The other time I faced it, the Flagship crushed me. It was sad.
And, yes, Samurai Flamenco is indeed some anime ass anime. (Or maybe some sentai ass anime.) It starts out semi-grounded and becomes gradually more sentai/anime by the episode. The process has been amusing to watch.