I 'd bet the next year or so is going be mostly business "as usual." I wouldn't expect any major shakeups for awhile. Long term though, I bet it's going to be radically different from how it is now. They'll hire new people- and I doubt they'll continue the trend of harvesting ex-Gamespot employees. That can only last so long. Jeff's said on a couple of occasions that he'd like the site to expand. Kessler, maybe? Who knows, because CBSi is a big corporation, business decisions tend to slowly crawl. Five years from now... Brad could actually leave- I could see him getting married and moving back home, if you're raising a family, it's nice to have some extended family around. Patrick, like Sara, might leave the site on good terms (long distance relationships are difficult, man, one-person quicklooks of old horror games can only entertain for so long.) As for short term. Will Vinnie take over as Bombcast host? Will Rorie move to editorial? This stuff wouldn't surprise me.
I feel that the only person in the crew who could host the bombcast would be Jeff at this point. If I am not mistaken, Jeff would take the reigns whenever Ryan was absent from the show. It seams like the logical fit.