Dave, the other outdated stuff here has been pointed out, though it would be fun to hear your opinions on those sequels. Also, it seems like Project Eternity is going to be the closest thing we'll ever get to a sequel for all that Infinity Engine stuff!

Deus Ex has one sequel and one prequel, Mafia have sequel. Better change that.

I'm not sure when you made this list, Dave, but we're in production on a sequel-of-sorts to Titan Quest. Iron Lore disbanded (read: "was destroyed by THQ"), but a bunch of us are building Grim Dawn now as Crate Entertainment.

http://www.grimdawn.com

Mafia has mafia II

Awesome list. Add somewhere Dungeon Keeper, and it will be more awesome.

This list confuses me

Nice list but very outdated as many of the games have sequels already :D 
 
Btw, the closest thing to a sequel to Titan Quest would be Grim Dawn by CRATE, the same guys who were laid off after Iron Lore disbanded. 
 
I'm sure you're aware of Mafia II, Deus Ex: Human Revolution, and even Dragon Age: Origins (spiritual sequel to Baldur's Gate).

I would humbly suggest that you also add Freelancer to your list. A great open world multiplayer sandbox game with customizable ships and an economy and all sorts of coolness. Looked gorgeous for the time, and has limitless potential that Microsoft just shelved. I know a lot of people that would be extremely interested in a sequel.

I saw Freespace 2 and thought... yes.

I think Colony Wars (PSX) needs a new modern sequel.

I always wondered why there wasn't a Worlds of Starcraft.

What a great list! I agree with you on most, I would definitely add Freelancer!!! Would kill for a sequel to that!

What about Psi-Ops: Mindgate Conspiracy?
Midway never made a sequel yet

Still think Mafia should have had a sequel Dave?

We really need a new Bully.

I agree we need more Freespace.  

Mafia II coming soon! Woot woot!

Not played a single one.
 
The game I've always wanted to see a sequel to is Rock 'n Roll Racing.

I haven't played most of these, but thumbs up for Alpha Centauri, Freespace 2, and Deus Ex.

Freedom Fighters...that is all.

My vote goes for Alpha Centauri... still one of my favorite games that I return to often. I'd like to finally get into Arcanum one day, I spent so much time making a character but could never get a hang of the combat. And as for World of Starcraft, that would be a wet dream. Heck, I would flunk out of college playing it.

You're such a PC gamer Dave. Freespace definitely needs another game

great list, I'll make one myself

Dude. 
Mutant League football. 
One of the seminal moments of my gaming life was using a brood-looking alien and exploding through a robot looking defender for a touchdown. 
Too true it's needs a sequel. 
Merry Xmas Dsnide.

I would love to see a sequel to Titan Quest.

FREESPACE 2. HOLY SHIT.   

There is a Mafia sequel in the works and it looks amazing.

Great list. Good to see the classic Outlaws get a mention. Man that game was/is awesome.

" I think old Planescape's lack of commercial success sort of dictated its never getting a sequel. "

I think old Planescape's lack of commercial success sort of dictated its never getting a sequel.  Too bad.  One of the most interesting, atmospheric games I've ever played.  Now I want to play it.
 
I would love to MAKE an infinity engine game, but I'd probably want to do something weird with it rather than doing the expected thing.  Had a fantasy about making a Buck Rogers conversion for it at one point.  Favorite part in the first BG was roaming the countryside.  Want to do something like that, but I wonder if there isn't a better engine for it...