NES - Super Mario Brothers 3 SNES - Super Mario World Genesis - Sonic 2 PS1 - Resident Evil N64 - Ocarina of Time PS2 - Grand Theft Auto 3 GameCube - Wind Waker Xbox - Halo
These are not nessecarly the "best" games for each console but they all had a huge impact when released, and for the most part hold up to the test of time. If you wanted to focus on the best split-screen multiplayer games this list would change quite a bit.
I like most other long-time RE fans am lowering my expectations in preparation for mild-to-severe disappointment. The only real problem I have is that we have yet to see a bad numerical RE game, and I'm starting to think this might break that trend.
Hopefully bad sales and reviews will lead to a RE2 remake? Without Mikami though who knows.
PS: I will still buy it day one to play it with my long time RE obsessed friend.